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Fuchs Research

Research about transplant, cell production, etc.

Cultivations in Lab May Usher in New Era for Corneal Transplants.  David Hwang, MD, a UCSF Director of ophthalmology is working on replicating corneal endothelial cells in vitro.  Not much has been done to re-implant them in donor cornea.

Cellular Transformation and the Extracellular Matrix in Corneal Wound  Healing. This is the Canadian research location where we think the cornea was cloned.

McMaster's University Chemical Engineering.
Research on artificial corneas.
Dr. H. Sheardown.

Review of Optometry Online taken from the Handbook of Ocular Disease Management.
A clinical description and discussion of Fuchs'. The print is small.

Clinical Specular Microscropy.
By Ronald A. Laing, Ph.D.
In Vivo Findings of Specular Microscopy.

National Center for Biotechnology Information
Extract from a National Institute of Health Database.  Links to many other medical and genetic databases.

"Fuchs' Endothelial Dystrophy--A fresh look at an aging disease," - which includes this statement of interest, "The current trend is to intervene surgically before the patient reaches the painful end-stage," and this

Oxford University (UK) Useful Vision Links.

JAMA archives
General Medical Search Facility

Merck's Manual of Diagnosis and Therapy
Brief description of Fuchs'
Then see this section which states that
one reason for corneal transplant is "to alleviate pain, e.g., to relieve the severe foreign-body sensation due to recurrent ruptured bullae in bullous keratopathy (pseudophakic, Fuchs' endothelial dystrophy, aphakic)."

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